Clinical studies and articles supporting EECPS safety and effectiveness

1

Michaels AD, Linnemeier G, Soran O, Kelsey SF, & Kennard ED. (2004). Two-Year Outcomes After Enhanced External Counterpulsation for Stable Angina Pectoris (from the International EECP Patient Registry [IEPR]). American Journal of Cardiology, 93, 461–464.

2

Arora RR, Chou TM, & Jain D, et al. (January, 2002). Effects of Enhanced External Counterpulsation on Health-Related Quality of Life Continue 12 Months After Treatment: A Substudy of the Multicenter Study of Enhanced External Counterpulsation. Journal of Investigative Medicine, 50(1), 25–32.

3

Taguchi I, Ogawa K, & Oida A, et al. (November 15, 2000). Comparison of Hemodynamic Effects of Enhanced External Counterpulsation and Intra-Aortic Balloon Pumping in Patients with Acute Myocardial Infarction. The American Journal of Cardiology, 86(10), 1139–1141.

4

Michaels AD, Accad M, & Ports TA, et al. (September 3, 2002). Left Ventricular Systolic Unloading and Augmentation of Intracoronary Pressure and Doppler Flow During Enhanced External Counterpulsation. Circulation, 106(10), 1237–1242.

5

Lawson WE, Hui JCK, & Cohn PF. (April, 2000). Long-Term Prognosis of Patients with Angina Treated with Enhanced External Counterpulsation: Five-Year Follow-Up Study. Clinical Cardiology, 23(4), 254–258.

6

Arora RR, Chou TM, & Jain D, et al. (June, 1999). The Multicenter Study of Enhanced External Counterpulsation (MUST-EECP): Effect of EECP on Exercise-Induced Myocardial Ischemia and Anginal Episodes. The Journal of the American College of Cardiology, 33(7), 1833–1840.

7

Soran O, Kennard ED, Holubkov R, Strobeck J, & Feldman AM. (2002). Enhanced External Counterpulsation as a Treatment for Chronic Angina Patients with Left Ventricular Dysfunction: A Report from the International EECP Patient Registry (IEPR). CHF, 8, 297–302.

8

Soran O. (January-February, 2004). A New Treatment Modality in Heart Failure. Cardiology In Review, 12(1), 15–20.

10

Lawson WE, KennardED, Holubkov R, Kelsey SF, Strobeck JE, Soran O, & Feldman AM. (2001). Benefit and Safety of Enhanced External Counterpulsation in Treating Coronary Artery Patients with a History of Congestive Heart Failure. Cardiology, 96, 78–84.

11

Kronhaus KD, & Lawson WE. (2002). Is Enhanced External Counterpulsation the Treatment Choice for Microvascular Angina? Journal of Investigative Medicine, 51(Suppl 2), S360 (26).

12

Crawford LE. (2002). Experience with Enhanced External Counterpulsation (EECP) in Coronary Artery Disease. Today’s Therapeutic Trends, 20(3), 243–252.

13

Linnemeier GC, Kennard ED, & Soran O, et al. (2003). Enhanced External Counterpulsation for the Relief of Angina in Patients With Diabetes: A One- Year Clinical Outcome Study. American Heart Journal, 146(3), 453–8.

14

Linnemeier G, et al. (2003). Enhanced External Counterpulsation in the Management of Angina in the Elderly. American Journal of Geriatric Cardiology, 12(2), 90–94.

15

Lawson WE, & Hui JCK. (November, 2000). Enhanced External Counterpulsation for Chronic Myocardial Ischemia. The Journal of Critical Illness, 15(11), 629–636.

16

Bonetti PO, et al. (June 4, 2003). Enhanced External Counterpulsation for Ischemic Heart Disease. Journal of the American College of Cardiology, 41(11), 1918–25.

17

Urano H, Ikeda H, & Ueno T, et al. (January, 2001). Enhanced External Counterpulsation Improves Exercise Tolerance, Reduces Exercise-Induced Myocardial Ischemia and Improves Left Ventricular Diastolic Filling in Patients with Coronary Artery Disease. Journal of the American College of Cardiology, 37(1), 93–99.

18

Urano H, Lida S, & Fukami K, et al. (October, 2000). Intermittent Shear Stimuli by Enhanced External Counterpulsation (EECP) Restores Endothelial Function in Patients with Coronary Artery Disease. Circulation, 102(18 Suppl 2), II–57(266).

19

Masuda D, Nohara R, & Hirai T, et al. (August, 2001). Enhanced External Counterpulsation Improved Myocardial Perfusion and Coronary Flow Reserve in Patients with Chronic Stable Angina; Evaluation by 13N-Ammonia Positron Emission Tomography. European Heart Journal, 22(16), 1451–1458.

20

WuGF, Qiang SZ, & Zheng ZS, et al. (1999). A Neurohormonal Mechanism for the Effectiveness of Enhanced External Counterpulsation. Circulation, 100(18), I-832(4390).

21

Feldman AM. (December, 2002). Enhanced External Counterpulsation: Mechanism of Action. Clinical Cardiology, 25(12 Suppl 2), II 11–15.

22

Bonetti PO, Barsness GW, & Keelan PC, et al. (May 21, 2003). Enhanced External Counterpulsation Improves Endothelial Function in Patients with Symptomatic Coronary Artery Disease. Journal of the American College of Cardiology, 41(10), 1761–1768.

23

Michaels AD, Kennard ED, & Kelsey SE, et al. (June, 2001). Does Higher Diastolic Augmentation Predict Clinical Benefit from Enhanced External Counterpulsation?: Data from the International EECP Patient Registry (IEPR). Clinical Cardiology, 24(6), 453–458.

24

Lakshmi M, KennardED, Kelsey SF, Holubkov R, & Michaels AD. (2002). Relation of the Pattern of Diastolic Augmentation During a Course of Enhanced External Counterpulsation (EECP) to Clinical Benefit [from the International EECP Patient Registry(IEPR)]. American Journal of Cardiology,

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